Deciphering molecular determinants of GPCR-G protein receptor interactions by complementary integrative structural biology methods
J.-G. Castel, Thomas Botzanowski, Ieva Vasiliauskaité-Brooks, Alexandre Frechard, Gilbert Bey, Marine Schroeter, Elise Del Nero, François Debaene, Fabrice Ciesielski, Denis Zeyer, Sarah Cianférani, Renaud Morales
This study uses cryo-EM and HDX-MS to analyze GPBAR1-G protein interactions, revealing conformational dynamics and structural details of the complex.
Scientific Reports · Aug 26, 2025Peer-reviewedBiophysics