Lipid Composition Controls the Huntingtin Exon1 Membrane-Association and Differentially Modulates its Flanking Regions Dynamics
Tânia Sousa, Goncalo Damas, Ana Coutinho, Nuno Bernardes, Ana Sofia Azevedo, Manuel J. E. PRIETO, Ana M. Melo
This study examines how lipid composition affects Httex1 membrane association and the dynamics of its flanking regions, revealing distinct behavior between the N17 and PRR domains.
Protein Science · May 14, 2026Peer-reviewedBiophysics