Loss of systemic anti-viral immunity and LMP1-driven suppressive myeloid tumour niches converge to shape the immunobiology of EBV+ diffuse large B-cell lymphoma
Éanna Fennell, Soi Cheng Law, Alexander C. Dowell, Matthew Pugh, Christina M. Enright, Aisling M. Ross, Aoife S. Hennessy, Ciara I. Leahy, Nadezhda Nikulina, Alex G Richter, Lucia Mundo, Lorenzo Leoncini, Stefano Lazzi, Maria Chiara Siciliano, Stefan D. Dojcinov, , Paul Gerard Murray
This study identifies systemic antiviral immune dysfunction and LMP1-driven suppressive myeloid niches as key factors shaping the immunobiology of EBV+ diffuse large B-cell lymphoma.
bioRxiv · Jan 28, 2026 · PreprintCancer Biology