Author

Ciara I. Leahy

University of LimerickORCID 0000-0002-6952-4924Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Aoife S. HennessyiD· 3 shared Éanna FennelliD· 3 shared Matthew PughiD· 3 shared Nadezhda NikulinaiD· 3 shared Paul Gerard MurrayiD· 3 shared Aisling M. RossiD· 2 shared Gerald NiedobitekiD· 2 shared Graham S. TayloriD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersCancer Biology

Aoife S. HennessyORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Loss of systemic anti-viral immunity and LMP1-driven suppressive myeloid tumour niches converge to shape the immunobiology of EBV+ diffuse large B-cell lymphoma

Éanna Fennell, Soi Cheng Law, Alexander C. Dowell, Matthew Pugh, Christina M. Enright, Aisling M. Ross, Aoife S. Hennessy, Ciara I. Leahy, Nadezhda Nikulina, Alex G Richter, Lucia Mundo, Lorenzo Leoncini, Stefano Lazzi, Maria Chiara Siciliano, Stefan D. Dojcinov, , Paul Gerard Murray

This study identifies systemic antiviral immune dysfunction and LMP1-driven suppressive myeloid niches as key factors shaping the immunobiology of EBV+ diffuse large B-cell lymphoma.

bioRxiv · Jan 28, 2026 · PreprintCancer Biology

The spatial landscape of infectious mononucleosis tonsils

Ciara I. Leahy, Matthew Pugh, Aoife S. Hennessy, Nadezhda Nikulina, Stefan D. Dojcinov, Gerald Niedobitek, Graham S. Taylor, Paul Gerard Murray, Éanna Fennell

This study creates the first multiomic single-cell spatial atlas of palatine tonsils in infectious mononucleosis, revealing EBV's epithelial tropism and immunosuppressive microenvironment.

bioRxiv · Oct 9, 2025 · PreprintImmunology

CellMAPS: A no-code model-based customisable multiplex image analysis workflow

Éanna Fennell, Colm Brandon, Steve Boßelmann, Stephen Ryan, Amandeep Singh, Aoife S. Hennessy, Aisling M. Ross, Ciara I. Leahy, Matthew Pugh, Nadezhda Nikulina, Oliver Braubach, Gerald Niedobitek, Graham S. Taylor, Tiziana Margaria, Paul Gerard Murray

CellMAPS provides a no-code, customizable multiplex image analysis workflow for non-specialists to perform image processing and spatial analyses across various diseases.

bioRxiv · Oct 7, 2025 · PreprintBioinformatics