Author

Grant Irons

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Aliyaa Pathan· 1 shared Change-he Shi· 1 shared Christina D’Ovidio· 1 shared Elena Vargas· 1 shared Ethan PaulаkonisiD· 1 shared Georgia RoperiD· 1 shared I W HwangiD· 1 shared I.-Wen PengiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Aliyaa Pathan

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1 paper

Recent·Most cited

Domain-specific decoupling of co-chaperone and ligase functions in STUB1 underlies biochemical and clinical heterogeneity in SCA48

Selin Altınok, Ethan Paulаkonis, Michael Fernandes de Almeida, I W Hwang, Rebekah Sanchez‐Hodge, Christina D’Ovidio, Georgia Roper, Grant Irons, Elena Vargas, I.-Wen Peng, Morcos Saeed, Aliyaa Pathan, Sarah M. Ronnebaum, Change-he Shi, Mark John Ranek, , Jonathan Cummings Schisler

This study identifies how STUB1 mutations in SCA48 disrupt co-chaperone and ligase functions in a domain-specific manner, leading to clinical heterogeneity.

bioRxiv · Nov 26, 2025 · PreprintNeuroscience