HPV16 neutralizing monoclonal antibodies show evidence for common developmental pathways and public epitopes
Joseph J. Carter, Nicholas K. Hurlburt, Erin M. Scherer, Suruchi Singh, Justas V. Rodarte, Robin A.J. Smith, Peter Lewis, Rachel Kinzelman, Jacqueline Kieltyka, Madelyn Cabán, Gregory C. Wipf, Marie Pancera, Denise A. Galloway
This study characterizes 70 HPV16-specific monoclonal antibodies, identifying common neutralization loops and shared developmental pathways among vaccine-induced antibodies.
bioRxiv · Mar 31, 2025 · PreprintImmunology