Denise A. Galloway

This paper develops an immunocompetent mouse model of Merkel cell carcinoma that forms tumors and metastases, showing that LSD1 inhibitors effectively reduce tumor growth and metastasis.

The paper shows that B cells specific for viral oncoproteins in Merkel cell carcinoma tumors predict long-term disease control and enhance T cell responses.

The paper identifies delta-catenin as essential for proliferation in virus-positive Merkel cell carcinoma cells but not in fibroblasts, revealing distinct roles in viral infection and tumorigenesis.

This study characterizes 70 HPV16-specific monoclonal antibodies, identifying common neutralization loops and shared developmental pathways among vaccine-induced antibodies.

This study shows that polyomavirus ALTOs, but not MTs, downregulate viral early gene expression by activating the NF-κB pathway, acting as tumor suppressors in Merkel cell carcinoma.

This study identifies MCPyV protein ALTO as a factor that modulates the STING-TBK1 pathway to limit viral replication and maintain persistent infection.