Enhancing Mycobacterial Clearance via Heterologous BCG Prime Boost Strategy Using Recombinant Mycobacterium smegmatis
HS Ji, KR Kang, JA Kim, Yh Kwon, Hyun Mi Kang, UY Choi, JH Kang, GS Choi
This study evaluates a recombinant Mycobacterium smegmatis booster vaccine with β-glucan adjuvant, showing improved systemic bacterial clearance compared to BCG revaccination in a TB mouse model.
bioRxiv · Sep 3, 2026 · PreprintImmunology