Unveiling the Role of PHF20 in TBC1D4-Mediated Glucose Uptake During Toxoplasma gondii Infection
Fei-Fei Gao, Xincheng Wang, Guan-Hao Hong, Yu-Sun Yun, In-Wook Choi, Jae–Min Yuk, Wei Zhou, Xintian Chen, Jongsun Park, Guang‐Ho Cha
This study identifies how Toxoplasma gondii enhances host glucose uptake via the PI3K/AKT-TBC1D4 pathway, promoting parasite proliferation and suggesting host glucose metabolism as a therapeutic target.
bioRxiv · Aug 8, 2025 · PreprintCell Biology