Guang Hu

Accurate Characterization of the Allosteric Energy Landscapes, Binding Hotspots and Long-Range Communications for KRAS Complexes with Effector Proteins : Integrative Approach Using Microsecond Molecular Dynamics, Deep Mutational Scanning of Binding Energetics and Allosteric Network Modeling

This study integrates molecular dynamics, mutational scanning, and network modeling to characterize KRAS-RAF1 binding hotspots, allostery, and conformational dynamics, revealing how oncogenic mutations alter binding affinity and signaling.

The ghr-miR164 and GhNAC100 module participates in cotton plant defence against Verticillium dahliae

The paper identifies miRNAs and their targets, including the ghr-miR164-GhNAC100 module, involved in cotton's defense against Verticillium dahliae.