Author

Guangming Xiang

Shanghai Jiao Tong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:graph neural network· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

Hongzhong LuiD· 3 shared Siwei HeiD· 2 shared Xingcun Fan· 2 shared Xuefeng YaniD· 2 shared Gengrong GaoiD· 1 shared Haoyu WangiD· 1 shared Le WangiD· 1 shared Liyun SuiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersBioinformatics

Hongzhong LuORCID

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3 papers

Recent·Most cited

Efficient Cell Factory Design by Combining Meta-Heuristic Algorithm with Enzyme Constrained Metabolic Models

Wenxing Liao, Gengrong Gao, Haoyu Wang, Xingcun Fan, Le Wang, Siwei He, Guangming Xiang, Xuefeng Yan, Hongzhong Lu

MetaStrain combines enzyme-constrained models with meta-heuristic algorithms to efficiently identify combinatorial gene targets for improving microbial product yields.

Bioresource Technology · Apr 23, 2026Peer-reviewedBioinformatics

Decoding yeast transcriptional regulation via a data- and mechanism-driven distributed large-scale network model

Xingcun Fan, Guangming Xiang, Wenbin Liao, Luchi Xiao, Siwei He, Na Luo, Hongzhong Lu, Xuefeng Yan

This paper introduces a distributed large-scale neural network model for yeast transcriptional regulation, capable of predicting dynamic regulatory relationships and identifying key transcription factors.

Synthetic and Systems Biotechnology · Jun 14, 2025Peer-reviewedBioinformatics

DeepEnzyme: a robust deep learning model for improved enzyme turnover number prediction by utilizing features of protein 3D structures

Tong Wang, Guangming Xiang, Siwei He, Liyun Su, Yuguang Wang, Xuefeng Yan, Hongzhong Lu

DeepEnzyme improves kcat prediction using Transformer and GCN with sequence and 3D structure features, showing robustness for low similarity enzymes and mutation impact analysis.

Briefings in Bioinformatics · Jul 25, 2024Peer-reviewedBioinformatics