Design of intrinsically disordered region binding proteins
Kejia Wu, Hanlun Jiang, Derrick R. Hicks, Caixuan Liu, Edin Muratspahić, Theresa A. Ramelot, Yuexuan Liu, Kerrie E. McNally, Sebastian Kenny, Andrei Mihut, Amit Gaur, Brian Coventry, Wei Chen, Asim K. Bera, Alex Kang, , David A. Baker
The paper designs proteins that bind intrinsically disordered regions with high affinity and specificity across diverse targets.
Science · Jul 17, 2025Peer-reviewedBiochemistry