Maximizing the productivity of co-transcriptional in vitro transcription
Wei He, Kunkun Zhang, Guiying Ji, Hongli Zhou, Ya Dai, Minghao Xu, Xiaoyu Xu, Qiuheng Jin
This study optimizes co-transcriptional in vitro transcription (co-IVT) to achieve high mRNA yield and quality, reducing impurities and improving production efficiency for therapeutic applications.
bioRxiv · Jul 29, 2026 · PreprintBioengineering