A high-throughput method for unbiased quantitation and categorisation of nuclear morphology
Benjamin Matthew Skinner, Claudia Cattoni Rathje, Joanne Bacon, Emma Elizabeth Philippa Johnson, Erica Lee Larson, Emily E. K. Kopania, Jeffrey Martin Good, Gullalaii Yousafzai, Nabeel Ahmed Affara, Peter J. I. Ellis
The paper develops a program to quantify and categorize nuclear morphology in mouse sperm, finding increased shape variability in lab lines compared to wild-derived lines and subtle cross-direction effects in F1 offspring.
Biology of Reproduction · Feb 11, 2019Peer-reviewedGenomics