Benjamin Matthew Skinner

Reduced baseline male fertility and increased sensitivity to hypoxic stress in high-elevation deer mice

This study finds that high-elevation deer mice have reduced baseline fertility and greater sensitivity to hypoxia compared to low-elevation mice, with gene expression changes suggesting adaptive testicular regression.

Refining sperm quality assessment by high-throughput nuclear morphometric analysis

This paper uses high-throughput nuclear morphometric analysis to assess pig sperm quality, finding significant differences in head morphology between standard and non-standard samples.

Explaining the counter-intuitive effectiveness of trophectoderm biopsy for PGT-A using computational modelling

The paper uses computational modeling to show that while biopsy results are poor predictors of individual embryo mosaicism, they can still be used to rank embryos for transfer in PGT-A.

An improved pig reference genome sequence to enable pig genetics and genomics research

The paper presents improved pig reference genomes using long-read sequencing, enhancing continuity and accuracy for pig genetics and genomics research.

Differential sperm motility mediates the sex ratio drive shaping mouse sex chromosome evolution

The paper shows that X-bearing sperm have greater motility than Y-bearing sperm in mice with Yq deletions, leading to a skewed sex ratio.

A conserved requirement for Fbxo7 during male germ cell cytoplasmic remodelling

This paper shows that Fbxo7 is required for male fertility in mice, as its deficiency leads to sterile males with abnormal spermatid disposal during spermiogenesis.

A high-throughput method for unbiased quantitation and categorisation of nuclear morphology

The paper develops a program to quantify and categorize nuclear morphology in mouse sperm, finding increased shape variability in lab lines compared to wild-derived lines and subtle cross-direction effects in F1 offspring.

Automated nuclear cartography reveals conserved sperm chromosome territory localization across 2 million years of mouse evolution

The paper develops an automated method to map FISH signals in sperm nuclei and finds conserved chromosome territory organization across mouse lineages.

Origin and phylogenetic status of the local Ashanti Dwarf pig (ADP) of Ghana based 1 on evidence from mtDNA analysis, MC1R, and Y-chromosome haplotypes

The paper investigates the origin and genetic diversity of the Ashanti Dwarf Pig using mtDNA, MC1R, Y-chromosome, and SNP data, revealing European and Asian genetic contributions.

The pig X and Y chromosomes: structure, sequence and evolution

This paper presents improved assemblies and gene annotations for the pig X and Y chromosomes, revealing evolutionary mechanisms and gene content differences compared to other mammals.

Expansion of the HSFY gene family in pig lineages

This study investigates the HSFY gene family in pigs and other suids, finding two amplified variants with potential roles in spermatogenesis and fertility.