Innovative Strategies for Enhancing Signal-to-Noise Ratio in Single-molecule Imaging: The Influence of Molecular Motion
Gayun Bu, Gyeongho Kang, Seongyu Park, Jae‐Hyung Jeon, Jong‐Bong Lee
This study shows that molecular motion enhances signal-to-noise ratio in single-molecule fluorescence imaging and proposes a method to increase the upper concentration limit of fluorophore-tagged biomolecules.
bioRxiv · Oct 13, 2024 · PreprintBiophysics