Loss of direct binding of Leishmania profilin with actin adversely affected its functions and interactions with other cellular proteins
Srikalaivani Raja, Prashant Kumar, H S, Sathish Thiyagarajan, Chhitar M. Gupta
This study shows that deleting the actin binding domain of Leishmania profilin impairs cell growth, vesicle trafficking, and mitochondrial function.
bioRxiv · Apr 17, 2025 · PreprintCell Biology