The evolution of non-motif selectivity determinants in Monosiga brevicollis PDZ domains
M. Gao, I. G. P. Mackley, S. Mesbahi-Vasey, H. A. Bamonte, S. A. Struyvenberg, L. Landolt, N. J. Pederson, L. I. Williams, C. D. Bahl, L. Brooks, J. F. Amacher
This study investigates the evolution of PDZ domain selectivity determinants in Monosiga brevicollis by analyzing crystal structures and binding affinities, finding conserved peptide selectivity with one exception.
bioRxiv · May 28, 2020Biochemistry