Author

S. A. Struyvenberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:non-human primate· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

M. Gao· 3 shared I. G. P. Mackley· 2 shared J. F. Amacher· 2 shared N. J. Pederson· 2 shared C. D. Bahl· 1 shared D. A. Johnson· 1 shared D. R. Madden· 1 shared E. F. Tahti· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBiochemistry

M. Gao

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3 papers

Recent·Most cited

Additive energetic contributions of multiple peptide positions determine the relative promiscuity of viral and human sequences for PDZ domain targets

E. F. Tahti, J. M. Blount, S. N. Jackson, M. Gao, N. P. Gill, S. N. Smith, N. J. Pederson, S. N. Rumph, S. A. Struyvenberg, I. G. P. Mackley, D. R. Madden, J. Amacher

bioRxiv · Dec 31, 2022Biochemistry

A second specificity-determining loop in Class A sortases: Biochemical characterization of natural sequence variation in chimeric SrtA enzymes

I. M. Piper, S. A. Struyvenberg, J. D. Valgardson, D. A. Johnson, M. Gao, K. Johnston, J. E. Svendsen, H. M. Kodama, K. L. Hvorecny, J. M. Antos, J. F. Amacher

The paper identifies a conserved loop in Class A sortases that influences substrate specificity and demonstrates how engineered chimeric enzymes can expand substrate tolerance.

bioRxiv · Mar 27, 2021Biochemistry

The evolution of non-motif selectivity determinants in Monosiga brevicollis PDZ domains

M. Gao, I. G. P. Mackley, S. Mesbahi-Vasey, H. A. Bamonte, S. A. Struyvenberg, L. Landolt, N. J. Pederson, L. I. Williams, C. D. Bahl, L. Brooks, J. F. Amacher

This study investigates the evolution of PDZ domain selectivity determinants in Monosiga brevicollis by analyzing crystal structures and binding affinities, finding conserved peptide selectivity with one exception.

bioRxiv · May 28, 2020Biochemistry