Inhibition of the mitochondrial permeability transition exerts sex-specific stimulatory effect on fracture repair
B. H. Shares, T.-J. Sheu, K. Schilling, R. Sautchuk, A. Paine, G. Beutner, L. C. Shum, C. O. Smith, E. Knapp, E. B. Brown, H. Awad, R. A. Eliseev
The paper shows that inhibiting CypD improves fracture repair in male mice but not females, with effects linked to mitochondrial function and β-catenin activity.
bioRxiv · Sep 18, 2019 · PreprintBiochemistry