β-adrenergic control of sarcolemmal CaV1.2 abundance by small GTPase Rab proteins
S. G. del Villar, T. L. Voelker, H. C. Spooner, E. J. Dickson, R. E. Dixon
This paper shows βAR activation increases sarcolemmal CaV1.2 channels via Rab4a and Rab11a-dependent endosomal trafficking, enhancing cardiac contractility.
bioRxiv · Sep 28, 2020Physiology