Author

H. Caohuy

Uniformed Services University of the Health Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2

Frequent Co-Authors

H. B. Pollard· 2 shared O. Eidelman· 2 shared Q. Yang· 2 shared T. Chen· 2 shared A. Bera· 1 shared B. S. Pollard· 1 shared Bette S. Pollard· 1 shared Dharmendra Kumar SoniiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersMicrobiology

H. B. Pollard

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Author profile →

3 papers

Recent·Most cited

PM2.5 toxin benzopyrene induces life-limiting inflammation and oxidative stress in the airway by up-regulation of TRPC6 and inactivation of β2AR/CFTR signaling

H. Caohuy, Ognoon Mungunsukh, Tinghua Chen, Qingfeng Yang, Thalia Dib, Bette S. Pollard, Naheed Fatima, Thomas Flagg, Dharmendra Kumar Soni, Roopa Biswas, William Rittase, Oliver J. L’Esperance, Sharon L. Juliano, Harvey B. Pollard

This study shows PM2.5 and its toxin benzo[a]pyrene induce airway inflammation and oxidative stress by up-regulating TRPC6 and inactivating β2AR/CFTR signaling.

bioRxiv · Apr 24, 2026 · PreprintPharmacology & Toxicology

Inflammation in the COVID-19 airway is due to inhibition of CFTR signaling by the SARS-CoV-2 Spike protein

H. Caohuy, O. Eidelman, T. Chen, Q. Yang, B. S. Pollard, N. I. Walton, H. B. Pollard

This paper shows that SARS-CoV-2 Spike protein inhibits CFTR signaling in airway epithelia, leading to inflammation similar to cystic fibrosis.

bioRxiv · Jan 18, 2022Microbiology

Common cardiac medications potently inhibit ACE2 binding to the SARS-CoV-2 Spike, and block virus penetration into human lung cells

H. Caohuy, O. Eidelman, T. Chen, Q. Yang, A. Bera, N. Walton, H. B. Pollard

This study shows cardiac medications like ouabain and digitoxin inhibit ACE2 binding to SARS-CoV-2 Spike and block virus entry into human lung cells.

bioRxiv · Jun 2, 2021Pharmacology & Toxicology