Human glioblastoma cell motility depends on the activity of the cysteine metabolism enzyme 3-Mercaptopyruvate sulfurtransferase
M. S. Saurty-Seerunghen, T. Daubon, L. Bellenger, V. Delaunay, G. Castro, J. Guyon, A. Rezk, S. Fabrega, A. Idbaih, F. Almairac, F. Burel-Vandenbos, L. Turchi, T. Virolle, J.-M. Peyrin, C. Antoniewski, , M.-P. Junier
The paper identifies MPST as a key driver of glioblastoma cell motility through oxidative stress regulation, validated using patient-derived models and in vivo experiments.
bioRxiv · Jan 21, 2022Cancer Biology