ESR1 fusion proteins invoke breast cancer subtype-dependent enrichment of ligand independent pro-oncogenic signatures and phenotypes
M. E. Yates, Z. Li, Y. Li, H. Guzolik, X. Wang, T. Liu, J. Hooda, J. M. Atkinson, A. V. Lee, S. Oesterreich
This study shows ER fusion proteins in breast cancer cell lines drive ligand-independent pro-oncogenic pathways, with subtype- and fusion-specific effects.
bioRxiv · Sep 18, 2023 · PreprintCancer Biology