Author

M. E. Yates

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. V. Lee· 4 shared S. Oesterreich· 4 shared J. M. Atkinson· 3 shared Z. Li· 3 shared D. D. Brown· 2 shared G. Tseng· 2 shared J. Carroll· 2 shared J. Chen· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersCancer Biology

A. V. Lee

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4 papers

Recent·Most cited

ESR1 fusion proteins invoke breast cancer subtype-dependent enrichment of ligand independent pro-oncogenic signatures and phenotypes

M. E. Yates, Z. Li, Y. Li, H. Guzolik, X. Wang, T. Liu, J. Hooda, J. M. Atkinson, A. V. Lee, S. Oesterreich

This study shows ER fusion proteins in breast cancer cell lines drive ligand-independent pro-oncogenic pathways, with subtype- and fusion-specific effects.

bioRxiv · Sep 18, 2023 · PreprintCancer Biology

EstroGene database reveals diverse temporal, context-dependent and directional estrogen receptor regulomes in breast cancer

Z. Li, T. Li, M. E. Yates, Y. Wu, A. Ferber, L. Chen, D. D. Brown, J. Carroll, M. J. Sikora, G. Tseng, S. Oesterreich, A. V. LEE

The paper establishes the EstroGene database, which compiles 246 experiments from 136 datasets to analyze estrogen receptor regulomes in breast cancer, revealing diverse temporal, context-dependent, and directional responses.

bioRxiv · Jan 30, 2023 · PreprintCancer Biology

Loss of E-cadherin Induces IGF1R Activation Revealing a Targetable Pathway in Invasive Lobular Breast Carcinoma

A. Elangovan, J. Hooda, L. Savariau, S. Puthanmadhomnarayanan, M. E. Yates, J. Chen, D. D. Brown, P. F. McAuliffe, S. Oesterreich, J. M. Atkinson, A. V. Lee

This study shows that loss of E-cadherin in ILC leads to increased IGF1R activation and sensitivity to inhibitors, suggesting a therapeutic target and biomarker for ILC.

bioRxiv · Feb 22, 2022 · PreprintCancer Biology

Hotspot ESR1 mutations are multimodal and contextual drivers of breast cancer metastasis

Z. Li, Y. Wu, M. E. Yates, N. Tasdemir, A. Bahreini, J. Chen, K. M. Levine, N. M. Priedigkeit, S. Ali, L. Buluwela, S. Arnesen, J. Gertz, J. K. Richer, B. Troness, D. El-Ashry, , S. Oesterreich

This study identifies ESR1 mutations as drivers of breast cancer metastasis by altering cell adhesion and migration through genomic and transcriptomic reprogramming.

bioRxiv · Feb 10, 2021 · PreprintCancer Biology