Adaptive radioresistance of Enterohemorrhagic Escherichia coli O157:H7 results in genomic loss of shiga toxin-encoding prophages
G. Gaougaou, A. T. Vincent, K. Krylova, H. Habouria, H. Bessaiah, A. Baraketi, F. J. Veyrier, C. M. Dozois, E. Deziel, M. Lacroix
This study shows that adaptive resistance of EHEC O157:H7 to gamma-irradiation involves loss of prophages encoding shiga toxins and mutations in specific genes, leading to reduced virulence and increased radioresistance.
bioRxiv · Aug 8, 2022 · PreprintMicrobiology