Analysis of allelic cross-reactivity of monoclonal IgG antibodies by a multiplexed reverse FluoroSpot assay
H. Hoffmann-Veltung, N. G. Anabire, M. F. Ofori, P. Janhmatz, N. Ahlborg, L. Hviid, M. d. P. Quintana
This study enhances the FluoroSpot assay to analyze monoclonal antibody cross-reactivity with allelic variants of the VAR2CSA antigen, demonstrating its utility in studying protective immunity to malaria.
bioRxiv · Apr 28, 2022Immunology