A single-dose intramuscular immunization of pigs with lipid-nanoparticle DNA vaccines based on the hemagglutinin antigen confers complete protection against challenge infection with the homologous influenza virus strain
T. N. Nguyen, S. Kumari, S. Sillman, J. Chaudhari, D. C. Lai, H. L. X. Vu
This study shows that lipid-nanoparticle DNA vaccines encoding hemagglutinin protect pigs fully against homologous IAV-S challenge with minimal viral shedding.
bioRxiv · Aug 22, 2023Microbiology