Cyclin E/CDK2 and feedback from soluble histone protein regulate the S phase burst of histone biosynthesis
C. Armstrong, V. J. Passanisi, H. M. Ashraf, S. L. Spencer
The paper identifies two mechanisms regulating histone biosynthesis during the cell cycle: CDK2-mediated phosphorylation of NPAT and soluble histone feedback on mRNA stability.
bioRxiv · Mar 17, 2023Cell Biology