TPX2 Amplification-Driven Aberrant Mitosis in Long-Term Cultured Human Embryonic Stem Cells
H.-C. Jeong, Y.-H. Go, J.-G. Shin, Y.-J. Kim, M.-G. Cho, D. Gwon, H. S. Cheong, H. Lee, J.-H. Lee, C.-Y. Jang, H. D. Shin, H.-J. Cha
The paper identifies TPX2 amplification in late-passaged hESCs as a driver of mitotic aberrations through transcriptome and genomic analysis.
bioRxiv · Feb 22, 2021 · PreprintCell Biology