An Unexpected Role of Neutrophils in Clearing Apoptotic Hepatocytes In Vivo
L. Cao, L. Ma, J. Zhao, X. Wang, X. Fang, W. Li, Y. Qi, Y. Tang, J. Liu, S. Peng, L. Yang, L. Zhou, L. Li, X. Hu, Y. Ji, , J. Xu
This study reveals that neutrophils, not macrophages, primarily clear apoptotic hepatocytes through a novel process called perforocytosis, and defects in this process contribute to autoimmune liver disease.
bioRxiv · Feb 8, 2023 · PreprintPhysiology