Author

H. Schiessel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 5

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 5 Approach:statistical model· 5 Assay:ChIP-seq· 1

Frequent Co-Authors

T. Yamamoto· 3 shared T. SAKAUE· 2 shared H. Merlitz· 1 shared J.-U. Sommer· 1 shared R. Blossey· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 2 mutual co-author links

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3 shared papersBiophysics

T. Yamamoto

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5 papers

Recent·Most cited

Loop extrusion driven volume phase transition of entangled chromosomes

T. Yamamoto, H. Schiessel

The paper develops a theory explaining how loop extrusion by condensin drives a volume phase transition in entangled chromosomes, leading to their collapse.

bioRxiv · Mar 18, 2022Biophysics

Polymer-Assisted Condensation: A Mechanism for Hetero-Chromatin Formation and Epigenetic Memory

J.-U. Sommer, H. Schiessel, H. Merlitz

The paper proposes a mechanism for heterochromatin formation and epigenetic memory through polymer-assisted condensation.

bioRxiv · Oct 13, 2021Biophysics

Slow chromatin dynamics enhances promoter accessibility to transcriptional condensates

T. YAMAMOTO, T. SAKAUE, H. Schiessel

The paper theoretically studies chromatin dynamics driven by loop extrusion to show that longer linker DNA increases promoter contact probability with transcriptional condensates when loop extrusion is active.

bioRxiv · Feb 16, 2021Biophysics

Phase separation of chromatin brush driven by enzymatic reaction dynamics of histone posttranslational modifications

T. YAMAMOTO, T. Sakaue, H. Schiessel

This study models chromatin phase separation in a chromatin brush system, showing that it occurs when the brush height drops below a threshold due to anti-correlation between activators and silencers.

bioRxiv · Nov 30, 2020 · PreprintBiophysics

Pioneer transcription factors in chromatin remodeling: the kinetic proofreading view

H. Schiessel, R. Blossey

The paper quantifies the role of pioneer transcription factors in chromatin remodeling using a kinetic proofreading model to compare remodeling efficiency based on binding and unbinding rates.

bioRxiv · Jan 24, 2020Biophysics