Cancer BiologybioRxiv
Efficacy and safety of glycosphingolipid SSEA-4 targeting CAR-T cells in an ovarian carcinoma model
H. Monzo, M. Hyytiäinen, E. Elbasani…·P. M. Ojala
This study evaluates anti-SSEA-4 CAR-T cells in ovarian cancer models, showing efficacy against SSEA-4 positive cells but highlighting dose-dependent toxicity.
DOI 10.1158/1535-7163.mct-23-0008