Author

P. M. Ojala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Haglund· 2 shared E. Elbasani· 2 shared J. Jukonen· 2 shared K. Tuohinto· 2 shared P. Laakkonen· 2 shared P. Saharinen· 2 shared S. Gramolelli· 2 shared A. Grundhoff· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersCancer Biology

C. Haglund

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

DLL4-Notch3-WNT5B axis is a novel mediator of bi-directional pro-metastatic crosstalk between melanoma and lymphatic endothelial cells

S. Alve, S. Gramolelli, J. Jukonen, S. Juteau, A. Pink, A. Manninen, E. Monto, M. H. Lackman, O. Carpen, S. Karaman, P. Saharinen, K. Vaahtomeri, P. M. Ojala

bioRxiv · Apr 21, 2023 · PreprintCancer Biology

Efficacy and safety of glycosphingolipid SSEA-4 targeting CAR-T cells in an ovarian carcinoma model

H. Monzo, M. Hyytiäinen, E. Elbasani, K. Kalander, J. Wall, L. Moyano-Galceran, J. Tanjore Ramanathan, J. Jukonen, P. Laakkonen, A. Ristimäki, J. Carlson, K. Lehti, S. Salehi, P. Puolakkainen, C. Haglund, , P. M. Ojala

This study evaluates anti-SSEA-4 CAR-T cells in ovarian cancer models, showing efficacy against SSEA-4 positive cells but highlighting dose-dependent toxicity.

bioRxiv · Sep 2, 2022Cancer Biology

KSHV infection of endothelial precursor cells with lymphatic characteristics as a novel model for translational Kaposis sarcoma studies

K. Tuohinto, T. A. DiMaio, E. A. Kiss, P. Laakkonen, P. Saharinen, T. Karnezis, M. Lagunoff, P. M. Ojala

This study identifies KSHV-infected lymphatic endothelial colony forming cells as a novel model for studying Kaposis sarcoma, showing their ability to persist in vivo and recapitulate tumor characteristics.

bioRxiv · Jul 25, 2022Microbiology

Oncogenic herpesvirus engages the endothelial transcription factors SOX18 and PROX1 to increase viral genome copies and virus production

S. Gramolelli, E. Elbasani, V. Nurminen, K. Tuohinto, T. Günther, R. E. Kallinen, S. P. Kaijalainen, R. Diaz, A. Grundhoff, C. Haglund, J. M. Ziegelbauer, M. Bower, M. Francois, P. M. Ojala

This study shows that SOX18 and PROX1, endothelial transcription factors, regulate KSHV lytic replication and virus production in lymphatic endothelial cells.

bioRxiv · Aug 27, 2019Microbiology