ImmunologybioRxiv
LILRB3 (ILT5) is a myeloid checkpoint on myeloid cells that elicits profound immununomodulation
M. Yeboah, C. Papagregoriou, D. C. Jones…·A. Roghanian
This study identifies LILRB3 as a myeloid checkpoint receptor that suppresses immune responses through agonistic monoclonal antibodies, showing immunosuppressive effects in vitro and in humanized mice.
DOI 10.1172/jci.insight.141593