Plus and minus ends of microtubule respond asymmetrically to kinesin binding by a long range directionally driven allosteric mechanism
H. T. Vu, Z. Zhang, R. Tehver, D. Thirumalai
This study investigates how kinesin binding induces directional asymmetry in microtubule structure through long-range allosteric effects, explaining the directionality of kinesin stepping.
bioRxiv · Aug 30, 2021 · PreprintBiophysics