Author

H. Tossavainen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

P. Permi· 2 shared C. Thapa· 1 shared D. Sauter· 1 shared F. Kirchhoff· 1 shared I. Pitkänen· 1 shared K. Saksela· 1 shared L. Antenucci· 1 shared M. Jartti· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

P. Permi

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2 papers

Recent·Most cited

Reassessing the substrate specificities of the major Staphylococcus aureus peptidoglycan hydrolases lysostaphin and LytM

L. Antenucci, S. Virtanen, C. Thapa, M. Jartti, I. Pitkänen, H. Tossavainen, P. Permi

This study uses NMR spectroscopy to determine the substrate specificities of lysostaphin and LytM, showing they prefer D-Ala-Gly cross-linked parts of peptidoglycan, with LytM also acting as a D-alanyl-glycine endopeptidase.

bioRxiv · Oct 13, 2023Biochemistry

Evolutionary plasticity of SH3 domain binding by Nef proteins of the HIV 1/SIVcpz lentiviral lineage

Z. Zhao, R. Fagerlund, D. Sauter, H. Tossavainen, P. Permi, F. Kirchhoff, K. Saksela

This paper shows that Nef proteins from HIV and SIV use different structural strategies, called R-clamps, to bind SH3 domains, with variations in amino acids at positions 83 and 120.

bioRxiv · Jun 22, 2021Microbiology