Author

L. Antenucci

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

P. Lappalainen· 2 shared P. Permi· 2 shared A. Isomursu· 1 shared A. Michelot· 1 shared A. Vizcaino-Castillo· 1 shared C. Thapa· 1 shared E. Kremneva· 1 shared E. T. Coffey· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

P. Lappalainen

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Reassessing the substrate specificities of the major Staphylococcus aureus peptidoglycan hydrolases lysostaphin and LytM

L. Antenucci, S. Virtanen, C. Thapa, M. Jartti, I. Pitkänen, H. Tossavainen, P. Permi

This study uses NMR spectroscopy to determine the substrate specificities of lysostaphin and LytM, showing they prefer D-Ala-Gly cross-linked parts of peptidoglycan, with LytM also acting as a D-alanyl-glycine endopeptidase.

bioRxiv · Oct 13, 2023Biochemistry

Unusual actin-binding mechanism and the role of profilin in actin dynamics of trypanosomatid parasites

A. Vizcaino-Castillo, T. Kotila, K. Kogan, R. Yanase, J. Como, L. Antenucci, A. Michelot, J. D. Sunter, P. Lappalainen

This study identifies a unique actin-binding mechanism of profilin in trypanosomatid parasites, revealing its role in actin dynamics and potential as a drug target.

bioRxiv · Jan 6, 2023 · PreprintBiochemistry

Conformational dynamics regulate SHANK3 actin and Rap1 binding

S. I. Salomaa, M. Miihkinen, E. Kremneva, I. Paatero, J. Lilja, G. Jacquemet, J. Vuorio, L. Antenucci, F. Hassani-Nia, P. Hollos, A. Isomursu, I. Vattulainen, E. T. Coffey, H.-J. Kreienkamp, P. Lappalainen, J. Ivaska

This study shows SHANK3 binds actin and Rap1 through its SPN domain, with conformational changes regulating this interaction and affecting cellular processes like filopodia formation and autism-related phenotypes.

bioRxiv · Nov 12, 2020 · PreprintCell Biology

Integrin cytoplasmic domain and pITAM compete for spleen tyrosine kinase binding

L. Antenucci, M. Hellman, V. P. Hytonen, P. Permi, J. Ylanne

The paper identifies distinct binding sites of integrin and pITAM to Syk's SH2 domains and shows they compete for binding.

bioRxiv · Jan 18, 2019 · PreprintBiochemistry