CISD3 is required for Complex I function, mitochondrial integrity, and skeletal muscle maintenance
H.-B. Marjault, O. Karmi, L. Rowland, T. T. Nguyen, D. Grant, C. Manrique-Acevedo, R. Nechushtai, R. Mittler
This study shows that CISD3 deficiency in mice causes muscle atrophy and mitochondrial dysfunction, revealing its role in Complex I function and muscle maintenance.
bioRxiv · Jun 3, 2023 · PreprintCell Biology