Structure-based identification of novel histone deacetylase 4 (HDAC4) inhibitors
R. Agarwal, P. Pattarawat, M. R. Duff, H.-C. R. Wang, J. Baudry, J. Smith
The paper identifies novel HDAC4 inhibitors using molecular modeling and in vivo testing, finding compounds that selectively target HDAC4 over other HDAC classes.
bioRxiv · May 31, 2022Cancer Biology