Pleiotropy of Bcl-2 family proteins is an ancient trait in the metazoan evolution
N. Popgeorgiev, L. Jabbour, T. T. M. Nguyen, N. Ralchev, R. Gadet, S. Manon, H.-J. Osigus, B. Schierwater, R. Rimokh, G. Gillet
This study identifies Bcl-2 family pleiotropy in Trichoplax adhaerens, showing dual roles in ER calcium regulation and mitochondrial apoptosis.
bioRxiv · Oct 24, 2019 · PreprintEvolutionary Biology