Noncanonical usage of stop codons in ciliates expands proteins with Q-rich motifs
C.-N. Chuang, H.-C. Liu, T.-T. Woo, H.-T. Hu, J.-L. Chao, C.-Y. Chen, Y.-P. Hsueh, T.-F. Wang
The paper identifies Q-rich motifs in proteins across eukaryotes and shows their expansion in ciliates due to noncanonical stop codon usage, which may prevent triplet repeat disorders.
bioRxiv · Dec 8, 2020Biochemistry