Glucocerebrosidase rescues alpha-synuclein from amyloid formation
M.S. Barber, H.M. Muller, R.G. Gilbert, A.J. Baldwin
This study shows that glucocerebrosidase inhibits lipid-induced alpha-synuclein amyloid formation and destabilizes existing fibrils through competitive binding of Syn termini.
bioRxiv · Jul 6, 2018 · PreprintBiophysics