DNA Methylation is stable after MMEJ and NHEJ double strand break repair
Ester Bnaya, Shay Shilo, Tzah Feldman, Tal Bacharach, Yoni Moskovitz, Aditee Kadam, Paz Yedidim, Hadas Azogy, Nathali Kaushansky, Noa Chapal-Ilani, Liran I. Shlush
The paper examines DNA methylation stability after MMEJ and NHEJ repair mechanisms, finding that methylation levels remain stable despite repair-induced deletions and in the presence of a DNMT3A mutation.
bioRxiv · Jul 21, 2022 · PreprintGenetics