The USH3A causative gene clarin1 functions in Muller glia to maintain retinal photoreceptors
Hannah J. T. Nonarath, Samantha L. Simpson, Tricia L. Slobodianuk, Hai Tran, Ross F. Collery, Astra Dinculescu, Brian A. Link
This study shows that Clrn1 in Muller glia is critical for photoreceptor maintenance in USH3A, with controlled expression required to prevent cell death and degeneration.
PLoS Genetics · Mar 11, 2025Peer-reviewedCell Biology