SIRT3-dependent mitochondrial oxidative stress in sodium fluoride-induced hepatotoxicity and salvage by melatonin
Chao Song, Jiamin Zhao, Jingcheng Zhang, Tingchao Mao, Beibei Fu, Haibo Wu, Yong Zhang
This study shows melatonin reduces fluoride-induced oxidative stress in HepG2 cells and mice by enhancing SIRT3 activity and PGC-1/ERR-mediated SIRT3 expression.
bioRxiv · Feb 11, 2017 · PreprintCell Biology