A steroid hormone regulates growth in response to oxygen availability
George P. Kapali, Viviane Callier, Hailey Broeker, Parth Tank, Samuel J. L. Gascoigne, Jon Fewell Harrison, Alexander W. Shingleton
This study shows that hypoxia reduces growth in Drosophila larvae through a systemic endocrine mechanism involving ecdysone and the insulin/IGF-signaling pathway.
bioRxiv · Jun 25, 2021 · PreprintDevelopmental Biology