NLRP3 inflammasome-related microglial pyroptosis in EcoHIV infected mice
Hailong Li, Charles F. Mactutus, Diego Altomare, Michael S. Shtutman, Rosemarie M. Booze
This study investigates the role of NLRP3 inflammasome and microglial pyroptosis in EcoHIV-infected mice, showing increased NLRP3 and GSDMD expression and reduced markers with MCC950 treatment.
bioRxiv · May 3, 2026 · PreprintNeuroscience