Spatial Single-Cell Mapping of Transcriptional Differences Across Genetic Backgrounds in Mouse Brains
Zachary Hemminger, Gabriela Sanchez-Tam, Haley De Ocampo, Aihui Wang, Thomas J Underwood, Fangming Xie, Qiuying Zhao, Dongyuan Song, Jingyi Jessica Li, Hong‐Wei Dong, Roy Wollman
The paper introduces ATLAS, a method to map transcriptional differences across genetic backgrounds in mouse brains, revealing significant cell type distribution changes between sexes and genetic models.
Nature Methods · Oct 30, 2026Peer-reviewedGenomics