Zhiqian Zhai

IntegrateRigor optimizes batch integration for cell identity recovery in single-cell and spatial transcriptomics data, revealing cancer-immune interface niches previously obscured by integration biases.

CIPHER optimizes aggregate spatial transcriptomics experiments by jointly designing gene signatures and cell embeddings, improving decoding accuracy and experimental reliability.

supCPM improves scRNA-seq visualization by preserving global structure and cluster variance using supervised clustering guidance.